First, you have to click over to LesFemmesTheTruth blog and read Susan Matthiesen’s fascinating write-up…
…of how applying Ivermectin horse paste to an elderly friend’s terrible dog bite (Dachshund) that was infected, that would not heal and was getting to be in danger of becoming something unthinkably bad not only healed it, but healed it FAST.
Our Nurse Claire provided the receipts on this: there is documentation in the medical literature of Ivermectin significantly accelerating healing of flesh wounds AND preventing scarring, which is quoted and linked below.
So, what I would do is try to get the horse paste for this usage, because the viscosity of the paste is perfect for application as a salve to a flesh wound. If you have the 1% injectable and can’t source any horse paste, I would soak a gauze pad in the 1% solution and apply as a poultice, with bandage dressing. And since Ivermectin is so inexpensive in the livestock forms, you can be aggressive in changing the salve or poultice and bandaging frequently.
Here is the paper that Nurse Claire sent, with the summary block quoted. Please note that a LOWER quantity of the Ivermectin cream used in this trial actually had better results. So just a light application to a wound is what you’re going for – not slathering.
It seems that Ivermectin’s known anti inflammatory properties are even more robust than we thought, and spills over into regrowth factor production stimulation. Amazing.
Also note that this research was done out of Ghana in West Africa – Kwame Nkrumah University of Science and Technology – where Ivermectin is as pedestrian as aspirin for both animals AND humans and has been for 35 years.
Please share this information aggressively, as flesh wounds do happen. Chances are that someone reading this right now will get some sort of cut, bite or burn at some point, or will have a close relative or friend who does, and this could make a massive difference, especially among the elderly or immunocompromised, as with Susan’s friend.
As always, I really hope this helps.
Wounds cause structural and functional discontinuity of an organ. Wound healing, therefore, seeks to re-establish the normal morphology and functionality through intertwined stages of hemostasis, inflammation, proliferation, and tissue remodelling. Ivermectin, a macrolide, has been used as an endectoparasiticide in human and veterinary medicine practice for decades. Here, we show that ivermectin exhibits wounding healing activity by mechanisms independent of its well-known antiparasitic activity. This study aimed to evaluate the wound healing property of ivermectin cream using histochemistry and enzyme-linked immunosorbent assay techniques.
Non-irritant dose of ivermectin cream (0.03–1%) decreased wound macroscopic indices such as exudation, edge edema, hyperemia, and granulation tissue deposition by day 9 compared to day 13 for the vehicle-treated group. This corresponded with a statistically significant wound contraction rate, hydroxyproline deposition, and a decreased time to heal rate. The levels of growth factors TGF-β1 and VEGF were significantly elevated on day 7 but decreased on day 21. This corresponded with changes in cytokines (IL-1α, IL-4, IL-10, and TNF-α) and eicosanoids (LTB4, PGE2, and PGD2) levels on days 7 and 21.. Interestingly, low doses of ivermectin cream (0.03–0.1%) induced wound healing with minimal scarring compared to higher doses of the cream and the positive control, Silver Sulfadiazine.
Ivermectin promotes wound healing partly through modulation of the inflammatory process and the levels of Transforming Growth Factor-Beta 1 and Vascular Endothelial Growth Factor. Low doses of ivermectin cream have the potential to be used in treating wounds with minimal scar tissue formation.